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Article

Glutathione S-transferase genotypes in systemic sclerosis and their association with clinical manifestations in early disease.

Genes and immunity - 1 Jun 2001

Tew M B, Reveille J D, Arnett F C, Friedman A W, McNearney T, Fischbach M, Ahn C, Tan F K

Abstract excerpt

The glutathione S-transferases (GSTs) are a family of enzymes involved in limiting oxidative damage to tissues. Null alleles for one or more of the GST enzymes, especially GSTM1, reportedly occur more frequently in patients with Sjögren's syndrome and systemic lupus erythematosus who possess cert...

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Source

Identifiers

PMID: 11477481
DOI: 10.1038/sj.gene.6363756

Genes

GSTM1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-11477481-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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