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Article

XRCC1 Arg399Gln and Arg194Trp polymorphisms and risk of systemic lupus erythematosus in an Iranian population: a pilot study.

BioMed research international - 1 Jan 2014

Salimi Saeedeh, Mohammadoo-Khorasani Milad, Tabatabai Ehsan, Sandoughi Mahnaz, Zakeri Zahra, Naghavi Anoosh

Abstract excerpt

BACKGROUND: Evidences are suggesting that DNA damage is implicated in development of systemic lupus erythematosus (SLE). Therefore we focused on two common XRCC1 polymorphisms (Arg399Gln and Arg194Trp) in SLE susceptibility in South East of Iran. METHODS: Peripheral blood DNA was extracted from 163 SLE patients and 180 healthy controls. PCR-restriction fragment length polymorphism method was used for genotyping...

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Identifiers

PMID: 24971336
DOI: 10.1155/2014/492956
PMCID: PMC4058225

Genes

XRCC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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