Article
Association of GSTT1, GSTM1 and CYP1A1 polymorphisms with susceptibility to systemic lupus erythematosus in the Chinese population.
Clinica chimica acta; international journal of clinical chemistry - 3 Jun 2010
Zhang Jufeng, Deng Jingui, Zhang Chao, Lu Yanxin, Liu Li, Wu Qi, Shao Yong, Zhang Jie, Yang Hong, Yu Bo, Wan Jun
Abstract excerpt
BACKGROUND: GSTT1, GSTM1, CYP1A1 are enzymes responsible for the detoxification of the toxicant which may be involved in the development of systemic lupus erythematosus (SLE). We examined the relationship between the risk of SLE and the polymorphisms of these genes in the Chinese population. METHODS: Samples from 298 SLE patients and 284 healthy controls were collected. Polymerase chain reaction-restriction...
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