Article
Distinct and sequential tissue-specific activities of the LIM-class homeobox gene Lim1 for tubular morphogenesis during kidney development.
Development (Cambridge, England) - 1 Jun 2005
Kobayashi Akio, Kwan Kin-Ming, Carroll Thomas J, McMahon Andrew P, Mendelsohn Cathy L, Behringer Richard R
Abstract excerpt
Kidney organogenesis requires the morphogenesis of epithelial tubules. Inductive interactions between the branching ureteric buds and the metanephric mesenchyme lead to mesenchyme-to-epithelium transitions and tubular morphogenesis to form nephrons, the functional units of the kidney. The LIM-class homeobox gene Lim1 is expressed in the intermediate mesoderm, nephric duct, mesonephric tubules, ureteric bud,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.