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Nephron Patterning: Lessons from Xenopus, Zebrafish, and Mouse Studies

11 Sept 2015

Abstract excerpt

The nephron is the basic structural and functional unit of the vertebrate kidney. To ensure kidney functions, the nephrons possess a highly segmental organization where each segment is specialized for the secretion and reabsorption of particular solutes. During embryogenesis, nephron progenitors undergo a mesenchymal-to-epithelial transition (MET) and acquire different segment-specific cell fates along the...

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PMID: 26378582
DOI: 10.3390/cells4030483

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