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Article

Notch Signaling in Kidney Development, Maintenance, and Disease

4 Nov 2019

Abstract excerpt

Kidney development involves formation of nephrons intricately aligned with the vasculature and connected to a branched network of collecting ducts. Notch signaling plays multiple roles during kidney development involving the formation of nephrons composed of diverse epithelial cell types arranged into tubular segments, all the while maintaining a nephron progenitor niche. Here, we review the roles of Notch...

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PMID: 31690016
DOI: 10.3390/biom9110692

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