Article
The basic-helix-loop-helix protein pod1 is critically important for kidney and lung organogenesis.
Development (Cambridge, England) - 1 Dec 1999
Quaggin S E, Schwartz L, Cui S, Igarashi P, Deimling J, Post M, Rossant J
Abstract excerpt
Epithelial-mesenchymal interactions are required for the development of all solid organs but few molecular mechanisms that underlie these interactions have been identified. Pod1 is a basic-helix-loop-helix (bHLH) transcription factor that is highly expressed in the mesenchyme of developing organs that include the lung, kidney, gut and heart and in glomerular visceral epithelial cells (podocytes). To determine the...
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