Article
Polymorphisms of thymidylate synthase in the 5'- and 3'-untranslated regions associated with risk of gastric cancer in South China: a case-control analysis.
Carcinogenesis - 1 Oct 2005
Zhang Zhengdong, Xu Yaochu, Zhou Jianwei, Wang Xinru, Wang Liwei, Hu Xu, Guo Jiangtao, Wei Qingyi, Shen Hongbing
Abstract excerpt
Fruits and certain vegetables have a protective effect on gastric cancer (GC) and folate is one of the nutrients in fruits and vegetables. We hypothesized that the polymorphisms of thymidylate synthase (TYMS) gene involved in folate metabolism are associated with GC risk. In a population-based case-control study of 337 GC cases and 326 controls, frequency-matched by age, sex and residential areas in a southern...
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