Article
Association of the thymidylate synthase polymorphisms with esophageal squamous cell carcinoma and gastric cardiac adenocarcinoma.
Carcinogenesis - 1 Dec 2004
Zhang Jianhui, Cui Yajing, Kuang Gang, Li Yan, Wang Na, Wang Rui, Guo Wei, Wen Denggui, Wei Lizhen, Yu Fengling, Wang Shijie
Abstract excerpt
Polymorphisms in the untranslated regions (UTRs) of the thymidylate synthase (TS) gene, which may modulate TS transcription and expression, have been associated with susceptibility and prognosis of several tumors. However, their effects on the development and clinical staging of esophageal squamous cell carcinoma (ESCC) and gastric cardiac adenocarcinoma (GCA) have not been assessed so far. In this study, the...
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