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Article

A new variant cytotoxic T lymphocyte escape mutation in HLA-B27-positive individuals infected with HIV type 1.

AIDS research and human retroviruses - 1 May 2005

Ammaranond Palanee, Zaunders John, Satchell Claudette, van Bockel David, Cooper David A, Kelleher Anthony D

Abstract excerpt

The immune response in HIV-infected individuals who carry HLA-B27 is characterized by an immunodominant cytotoxic T lymphocyte (CTL) response to a conserved epitope corresponding to amino acids 263-272 of HIV-1 p24 gag. The arginine at position 264 is a crucial anchor residue. Amino acid substitution at 264 from arginine (R) to glycine (G), lysine (K), or threonine (T) results in a low affinity peptide that binds...

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Share to Epitopes, T-Lymphocyte
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HIV Core Protein p24

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Share to T-Lymphocytes, Cytotoxic

Source

Identifiers

PMID: 15929701
DOI: 10.1089/aid.2005.21.395

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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