Article
Polymorphism of alcohol dehydrogenase, alcohol and aldehyde dehydrogenase activities: implication in alcoholic cirrhosis in white patients. The French Group for Research on Alcohol and Liver.
Hepatology (Baltimore, Md.) - 1 Jun 1992
Poupon R E, Nalpas B, Coutelle C, Fleury B, Couzigou P, Higueret D
Abstract excerpt
Two types of factors can theoretically modulate alcohol metabolism toward increased acetaldehyde production. These factors are the following: (a) individual, genetically determined isoenzymes with distinct catalytic properties, and (b) modifications of enzyme activity induced by alcohol itself or...
Topics
- Adult
- Aged
- Alcohol Dehydrogenase
- Alcoholism
- Aldehyde Dehydrogenase
- Female
- Humans
- Isoenzymes
- Liver
- Liver Cirrhosis
- Liver Cirrhosis, Alcoholic
- Male
- Middle Aged
- Phenotype
- Polymorphism, Genetic
- White People