Article
Genetic polymorphism of liver alcohol dehydrogenase in Spanish subjects: significance of alcohol consumption and liver disease.
Alcohol and alcoholism (Oxford, Oxfordshire) - 1 Nov 1994
Parés X, Farrés J, Parés A, Soler X, Panés J, Ferré J L, Caballería J, Rodés J
Abstract excerpt
Class I alcohol dehydrogenase (ADH) phenotypes have been studied by starch gel electrophoresis and activity analysis in liver tissue obtained at necropsy from 61 non-alcoholic subjects with normal liver (controls), and in biopsies from 60 chronic alcoholics with liver disease and from 24 subjects with non-alcoholic liver disease. Twenty-three per cent of controls exhibited the ADH2 phenotype, which represents the...
Topics
- Alcohol Dehydrogenase
- Alleles
- Biopsy
- Chromosome Mapping
- Cross-Cultural Comparison
- Gene Frequency
- Genetics, Population
- Isoenzymes
- Liver
- Liver Diseases, Alcoholic
- Phenotype
