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Article

Alcohol and acetaldehyde dehydrogenase gene polymorphism and alcoholism.

EXS - 1 Jan 1994

Sherman D I, Ward R J, Yoshida A, Peters T J

Abstract excerpt

Inherited variations in alcohol and aldehyde dehydrogenases, the principal enzymes of ethanol metabolism, have been implicated in determining susceptibility to alcoholism and alcohol-related organ damage. An association between an RFLP for the alcohol dehydrogenase-2 (ADH2) gene and alcohol-induced liver damage was demonstrated in a Caucasian population. Genotyping studies revealed an increase in the ADH3(2)...

Topics

Alcohol Dehydrogenase
Alcoholism
Aldehyde Oxidoreductases
Alleles
Amino Acid Sequence
Base Sequence
Gene Frequency
Genetic Variation
Genotype
Humans
Isoenzymes
Liver Diseases, Alcoholic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Point Mutation

Polymorphism, Genetic

Polymorphism, Restriction Fragment Length

White People

Source

Identifiers

PMID: 7913353
DOI: 10.1007/978-3-0348-7330-7_29

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7913353-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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