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Article

Alcohol and acetaldehyde dehydrogenase gene polymorphism and alcoholism.

EXS - 1 Jan 1994

Sherman D I, Ward R J, Yoshida A, Peters T J

Abstract excerpt

Inherited variations in alcohol and aldehyde dehydrogenases, the principal enzymes of ethanol metabolism, have been implicated in determining susceptibility to alcoholism and alcohol-related organ damage. An association between an RFLP for the alcohol dehydrogenase-2 (ADH2) gene and alcohol-induced liver damage was demonstrated in a Caucasian population. Genotyping studies revealed an increase in the ADH3(2)...

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PMID: 7913353
DOI: 10.1007/978-3-0348-7330-7_29

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