Article
[Determination of alcohol dehydrogenase genotype: no correlation between isoenzyme pattern and liver cirrhosis].
Schweizerische medizinische Wochenschrift - 14 Dec 1991
Wermuth B, Ernst E, von Wartburg J P, Speck R, Schwarzenbach F, Lauterburg B
Abstract excerpt
Mounting evidence from various fields of research links the oxidation product of alcohol, acetaldehyde, with the development of alcohol abuse-related pathology. One factor governing the production of acetaldehyde is the genetically determined pattern of class I alcohol dehydrogenase isoenzymes, consisting of "fast" beta 2 and gamma 1 and "slow" beta 1 and gamma 2 subunits. Alcoholics carrying the beta 2 and gamma...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.