Article
[Determination of alcohol dehydrogenase genotype: no correlation between isoenzyme pattern and liver cirrhosis].
Schweizerische medizinische Wochenschrift - 14 Dec 1991
Wermuth B, Ernst E, von Wartburg J P, Speck R, Schwarzenbach F, Lauterburg B
Abstract excerpt
Mounting evidence from various fields of research links the oxidation product of alcohol, acetaldehyde, with the development of alcohol abuse-related pathology. One factor governing the production of acetaldehyde is the genetically determined pattern of class I alcohol dehydrogenase isoenzymes, c...
Topics
- Alcohol Dehydrogenase
- Amino Acid Sequence
- Arthritis, Rheumatoid
- Genotype
- Hepatitis, Chronic
- Humans
- Isoenzymes
- Liver Diseases, Alcoholic
- Molecular Sequence Data
- Polymerase Chain Reaction
