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Article

The CARD-carrying caspase Dronc is essential for most, but not all, developmental cell death in Drosophila.

Development (Cambridge, England) - 1 May 2005

Xu Dongbin, Li Ying, Arcaro Michael, Lackey Melinda, Bergmann Andreas

Abstract excerpt

The initiator caspase Dronc is the only Drosophila caspase that contains a caspase activation and recruitment domain (CARD). Although Dronc has been implicated as an important effector of apoptosis, the genetic function of dronc in normal development is unclear because dronc mutants have not been available. In an EMS mutagenesis screen, we isolated four point mutations in dronc that recessively suppress the eye...

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Identifiers

PMID: 15800001
DOI: 10.1242/dev.01790
PMCID: PMC2519871

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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