Article
EPCR gene A3 haplotype and elevated soluble endothelial protein C receptor (sEPCR) levels in Turkish pediatric stroke patients.
Thrombosis research - 1 Jan 2007
Ulu Arzu, Gunal Denizay, Tiras Serap, Egin Yonca, Deda Gülhis, Akar Nejat
Abstract excerpt
INTRODUCTION: High plasma levels of sEPCR lead to dysfunction of the EPCR-mediated coagulation. We have evaluated the role of EPCR A3 haplotype with its representative promoter variant 1651 C-G in a total of twenty-seven pediatric stroke patients and fifty-nine healthy subjects. MATERIALS AND METHODS: Genotyping of the A3 haplotype was performed with RFLP analysis. Plasma sEPCR levels were measured with ELISA....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
