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Article

Conditional inactivation of the mouse Hus1 cell cycle checkpoint gene.

Genomics - 1 Aug 2005

Levitt Peter S, Liu Houchun, Manning Charlene, Weiss Robert S

Abstract excerpt

The Hus1 cell cycle checkpoint protein plays a central role in genome maintenance by mediating cellular responses to DNA damage and replication stress. Targeted deletion of mouse Hus1 results in spontaneous chromosomal abnormalities and embryonic lethality. To study the physiological impact of Hu...

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Identifiers

PMID: 15919177
DOI: 10.1016/j.ygeno.2005.04.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-15919177-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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