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Article

Identification of a novel apical sorting motif and mechanism of targeting of the M2 muscarinic acetylcholine receptor.

The Journal of biological chemistry - 17 Nov 2006

Chmelar Renée S, Nathanson Neil M

Abstract excerpt

Previous studies have shown that the M2 receptor is localized at steady state to the apical domain in Madin-Darby canine kidney (MDCK) epithelial cells. In this study, we identify the molecular determinants governing the localization and the route of apical delivery of the M2 receptor. First, by confocal analysis of a transiently transfected glycosylation mutant in which the three putative glycosylation sites...

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PMID: 16968700
DOI: 10.1074/jbc.M605954200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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