Article
Development of a monkey model for the study of primate genomic imprinting.
Molecular human reproduction - 1 Jun 2005
Fujimoto A, Mitalipov S M, Clepper L L, Wolf D P
Abstract excerpt
An understanding of the role of imprinted genes in primate development requires the identification of suitable genetic markers that allow analysis of allele-specific expression and methylation status. Four genes, NDN (Necdin), H19, SNRPN and IGF2, known to be imprinted in mice and humans, were selected for study in rhesus monkeys along with two imprinting centres (ICs) associated with the regulation of H19/IGF2,...
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