Article
Use of a novel system for defining a gene imprinting region.
Biochemical and biophysical research communications - 29 Oct 1993
Rachmilewitz J, Gonik B, Goshen R, Ariel I, Schneider T, de Groot N, Hochberg A
Abstract excerpt
Gene imprinting involves the expression of a single allele, depending on its parental origin. In this report, we describe the use of a novel system, implementing human tissues exclusively endowed with either maternally or paternally inherited chromosomes, to better define a known gene imprinting region. Specific RNA transcripts for Placental Ribonuclease Inhibitor (PRI) and Cathepsin D were analysed by northern...
Topics
- Alleles
- Blotting, Northern
- Cathepsin D
- Chromosomes, Human, Pair 11
- Female
- Gene Expression
- Humans
- Hydatidiform Mole
- Male
- Placenta
- Pregnancy
- Pregnancy Trimester, First