Article
Aberrant genomic imprinting in rhesus monkey embryonic stem cells.
Stem cells (Dayton, Ohio) - 1 Mar 2006
Fujimoto Akihisa, Mitalipov Shoukhrat M, Kuo Hung-Chih, Wolf Don P
Abstract excerpt
Genomic imprinting involves modification of a gene or a chromosomal region that results in the differential expression of parental alleles. Disruption or inappropriate expression of imprinted genes is associated with several clinically significant syndromes and tumorigenesis in humans. Additionally, abnormal imprinting occurs in mouse embryonic stem cells (ESCs) and in clonally derived animals. Imprinted gene...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
