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Article

The human necdin gene, NDN, is maternally imprinted and located in the Prader-Willi syndrome chromosomal region

1 Nov 1997

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Share to Epigenetics and DNA Methylation
Share to Genetic Syndromes and Imprinting
Share to Prenatal Screening and Diagnostics

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 9354807
DOI: 10.1038/ng1197-357

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Related research

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The human necdin gene, NDN, is maternally imprinted and located in the Prader-Willi syndrome chromosomal regionPMID 9354807Read ↗

Expression and imprinting of MAGEL2 suggest a role in Prader-willi syndrome and the homologous murine imprinting phenotype.Semantic proximity Read ↗

The Necdin Gene is Deleted in Prader-Willi Syndrome and is Imprinted in Human and MouseSemantic proximity Read ↗

The mouse Necdin gene is expressed from the paternal allele only and lies in the 7C region of the mouse chromosome 7, a region of conserved synteny to the human Prader-Willi syndrome region.Semantic proximity Read ↗

Necdin, a Prader-Willi syndrome candidate gene, regulates gonadotropin-releasing hormone neurons during developmentSemantic proximity Read ↗

A necdin/MAGE-like gene in the chromosome 15 autism susceptibility region: expression, imprinting, and mapping of the human and mouse orthologues.Semantic proximity Read ↗

Loss of the Prader-Willi syndrome protein necdin causes defective migration, axonal outgrowth, and survival of embryonic sympathetic neurons.Semantic proximity Read ↗

Disruption of the mouse necdin gene results in early post-natal lethality.Semantic proximity Read ↗

Functional domains of necdin for protein-protein interaction, nuclear matrix targeting, and cell growth suppression.Semantic proximity Read ↗

NSCL-1 and NSCL-2 synergistically determine the fate of GnRH-1 neurons and control necdin gene expression.Semantic proximity Read ↗

Systematic screening for mutations in the human necdin gene (NDN): identification of two naturally occurring polymorphisms and association analysis in body weight regulation.Semantic proximity Read ↗

Necdin-deficient mice do not show lethality or the obesity and infertility of Prader-Willi syndromeSemantic proximity Read ↗

Evolution of the DAN gene family in vertebratesSemantic proximity Read ↗

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