Article
High affinity nucleocapsid protein binding to the muPsi RNA packaging signal of Rous sarcoma virus.
Journal of molecular biology - 24 Jun 2005
Zhou Jing, McAllen John K, Tailor Yogita, Summers Michael F
Abstract excerpt
The genomes of all retroviruses contain sequences near their 5' ends that interact with the nucleocapsid domains (NC) of assembling Gag proteins and direct their packaging into virus particles. Retroviral packaging signals often occur in non-contiguous segments spanning several hundred nucleotides of the RNA genome, confounding structural and mechanistic studies of genome packaging. Recently, a relatively short,...
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