Article
A new hexose transporter from Cryptococcus neoformans: molecular cloning and structural and functional characterization.
Fungal genetics and biology : FG & B - 1 Jul 2005
Chikamori Minoru, Fukushima Kazutaka
Abstract excerpt
We carried out a screen for Cryptococcus neoformans genes involved in resistance to copper ion toxicity and identified a new hexose transporter (Hxt) gene, HXT1. Hxt1 consists of 520 amino acids and functions to transport hexoses such as glucose. Although Hxt1 conferred copper resistance to Saccharomyces cerevisiae, disruption of the HXT1 gene showed that Hxt1 is not necessary for copper resistance. In virulence...
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