Article
Xylose donor transport is critical for fungal virulence.
PLoS pathogens - 1 Jan 2018
Li Lucy X, Rautengarten Carsten, Heazlewood Joshua L, Doering Tamara L
Abstract excerpt
Cryptococcus neoformans, an AIDS-defining opportunistic pathogen, is the leading cause of fungal meningitis worldwide and is responsible for hundreds of thousands of deaths annually. Cryptococcal glycans are required for fungal survival in the host and for pathogenesis. Most glycans are made in the secretory pathway, although the activated precursors for their synthesis, nucleotide sugars, are made primarily in...
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