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Article

The glucose sensor-like protein Hxs1 is a high-affinity glucose transporter and required for virulence in Cryptococcus neoformans.

PloS one - 1 Jan 2013

Liu Tong-Bao, Wang Yina, Baker Gregory M, Fahmy Hany, Jiang Linghuo, Xue Chaoyang

Abstract excerpt

Cryptococcus is a major fungal pathogen that frequently causes systemic infection in patients with compromised immunity. Glucose, an important signal molecule and the preferred carbon source for Cryptococcus, plays a critical role in fungal development and virulence. Cryptococcus contains more than 50 genes sharing high sequence homology with hexose transporters in Saccharomyces cerevisiae. However, there is no...

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Identifiers

PMID: 23691177
DOI: 10.1371/journal.pone.0064239
PMCID: PMC3653957

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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