Article
Interleukin-2 gene polymorphisms associated with increased risk of gastric atrophy from Helicobacter pylori infection.
Helicobacter - 1 Jun 2005
Togawa Shozo, Joh Takashi, Itoh Makoto, Katsuda Nobuyuki, Ito Hidemi, Matsuo Keitaro, Tajima Kazuo, Hamajima Nobuyuki
Abstract excerpt
BACKGROUND: Gastric atrophy induced by Helicobacter pylori is thought to predispose patients to noncardiac gastric cancer development. However, the host genetic factors that influence the progression of gastric atrophy have not been elucidated. In this study, we examined the effects of cytokine polymorphisms on H. pylori-induced gastric atrophy. METHODS: Blood samples were taken from 454 Japanese subjects. The...
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