Associations between a PTPN11 polymorphism and gastric atrophy--opposite in Uzbekistan to that in Japan.

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Associations between a PTPN11 polymorphism and gastric atrophy--opposite in Uzbekistan to that in Japan.

Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2000

Hamajima Nobuyuki, Rahimov Bakhodir, Malikov Yusuf, Abdiev Shavkat, Ahn Keun Soo, Bahramov Saidkarim, Kawai Sayo, Nishio Kazuko, Naito Mariko, Goto Yasuyuki

Abstract excerpt

Src homology 2 domain-containing protein tyrosine phosphatase-2 (SHP-2) of gastric epithelial cells interacts with cagA from Helicobacter pylori (H. pylori). Our previous studies found the AA genotype of a G/A single nucleotide polymorphism at intron 3 (rs2301756) of PTPN11 gene, which encodes SHP-2, to be associated with a lower risk of gastric atrophy. The present study aimed to examine the association with...

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PMID: 18712962

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PTPN11

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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