Article
Novel interleukin-4 and interleukin-1 receptor antagonist gene variations associated with non-cardia gastric cancer in Japan: comprehensive analysis of 207 polymorphisms of 11 cytokine genes.
Journal of gastroenterology and hepatology - 1 May 2007
Seno Hiroshi, Satoh Kiichi, Tsuji Shingo, Shiratsuchi Takayuki, Harada Yosuke, Hamajima Nobuyuki, Sugano Kentaro, Kawano Sunao, Chiba Tsutomu
Abstract excerpt
BACKGROUND AND AIM: Helicobacter pylori (H. pylori)-induced chronic atrophic gastritis is a high-risk factor for gastric cancer. Immune responses to H. pylori are involved in gastric mucosal inflammation, and might affect clinical outcome, including the development of gastric cancer. The present study examines the significance of gene polymorphisms of various cytokines in the development of gastric cancer...
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