Article
Pleiotrophin mediates the neurotrophic effect of cyclic AMP on dopaminergic neurons: analysis of suppression-subtracted cDNA libraries and confirmation in vitro.
Experimental neurology - 1 Jul 2005
Mourlevat Sophie, Debeir Thomas, Ferrario Juan E, Delbe Jean, Caruelle Daniele, Lejeune Olivier, Depienne Christel, Courty José, Raisman-Vozari Rita, Ruberg Merle
Abstract excerpt
To better understand the particular vulnerability of mesencephalic dopaminergic neurons to toxins or gene mutations causing parkinsonism, we have taken advantage of a primary cell culture system in which these neurons die selectively. Antimitotic agents, such as cytosine arabinoside or cAMP, prev...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
