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Article

Non-antagonistic relationship between mitogenic factors and cAMP in adult Schwann cell re-differentiation.

Glia - 1 Jul 2009

Monje Paula V, Rendon Sayuri, Athauda Gagani, Bates Margaret, Wood Patrick M, Bunge Mary Bartlett

Abstract excerpt

The expression of myelination-associated genes (MGs) can be induced by cyclic adenosine monophosphate (cAMP) elevation in isolated Schwann cells (SCs). To further understand the effect of known SC mitogens in the regulation of SC differentiation, we studied the response of SCs isolated from adult nerves to combined cAMP, growth factors, including neuregulin, and serum. In adult SCs, the induction of MGs by cAMP...

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Identifiers

PMID: 19053056
DOI: 10.1002/glia.20819
PMCID: PMC2829776

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Source receipt: pubmed, retrieved 7 Sept 2026.

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