Article
Establishment and characterization of continuous hematopoietic progenitors-derived pig normal mast cell lines.
Life sciences - 1 Jul 2005
Femenia Françoise, Arock Michel, Leriche Laurence, Delouis Claude, Millet Gaëlle, Ben Hamouda Nadine, Cote Martine, Alliot Annie, Lilin Thomas, Pinton Alain, Iannucceli Nathalie, Parodi André Laurent, Boireau Pascal
Abstract excerpt
Mast cells (MCs) are tissue resident, hematopoietic stem cells-derived elements, distributed throughout the body. They are the pivotal mediating cells of allergic reactions. In addition, in mice, MCs play a critical role in the defense against several pathogens, such as bacteria, parasites and viruses. Whereas the biology of rodent and human MCs has been extensively studied using in vitro derived populations, the...
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