Article
Hemopoietic cells with features of the mast cell and basophil lineages and their potential role in allergy.
Current drug targets. Inflammation and allergy - 1 Dec 2003
Wang Jing, Qi Jian Cheng, Konecny Pam, Krilis Steven A
Abstract excerpt
Human mast cells (MCs) and basophils play a key role in the pathogenesis of allergic disorders, not only by producing inflammatory and fibrogenic mediators, but also by directly and indirectly secreting various cytokines and chemokines. Although mast cells and basophils have differences in many properties, recent evidence suggests that human MCs and basophils may be derived from a common progenitor, and their...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.