Article
Interleukin-6 polymorphism: a genetic risk factor for cardiac transplant related coronary vasculopathy?
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation - 1 May 2005
Densem Cameron G, Ray Michele, Hutchinson Ian V, Yonan Nizar, Brooks Nicholas H
Abstract excerpt
AIMS: Interleukin- (IL-) 6 is a pleiotropic cytokine with effects on the acute phase response, inflammation, and vascular function. A G to C polymorphism has been described at position -174 in the promoter region of the IL-6 gene. We investigated the influence of this polymorphism on the development of cardiac transplant related coronary vasculopathy (CV). METHODS: Sequence specific polymerase chain reaction...
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