Article
The interleukin-6 -147 g/c polymorphism is associated with increased risk of coronary artery disease in young South African Indian men.
Metabolic syndrome and related disorders - 1 Jun 2013
Phulukdaree Alisa, Khan Sajidah, Ramkaran Prithiksha, Govender Rishalan, Moodley Devapregasan, Chuturgoon Anil A
Abstract excerpt
BACKGROUND: Interleukin-6 (IL-6) is a proinflammatory cytokine involved in the pathogenesis of chronic inflammatory diseases such as coronary artery disease (CAD). The -174 IL-6 G/C promoter polymorphism influences mRNA levels and protein expression and is implicated in CAD. The Indian population in South Africa, unlike the black community, has a high prevalence of premature CAD. This polymorphism has not been...
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