Article
Donor and recipient-transforming growth factor-beta 1 polymorphism and cardiac transplant-related coronary artery disease.
Transplant immunology - 1 Nov 2004
Densem C G, Hutchinson I V, Yonan N, Brooks N H
Abstract excerpt
BACKGROUND: Transforming growth factor-beta1 (TGF-beta1) has been implicated in the pathogenesis of coronary vasculopathy following cardiac transplantation. The TGFB1 gene contains polymorphisms at positions +915* (Arg25Pro) and +869* (Leu10Pro) which may influence TGF-beta1 expression. We investigated the relationship between the development of coronary vasculopathy and the prevalence of these alleles in a...
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