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Article

Study of a new PPARgamma2 promoter polymorphism and haplotype analysis in a French population.

Molecular genetics and metabolism - 1 Jun 2005

Meirhaeghe Aline, Tanck Michael W T, Fajas Lluis, Janot Caroline, Helbecque Nicole, Cottel Dominique, Auwerx Johan, Amouyel Philippe, Dallongeville Jean

Abstract excerpt

Peroxisome proliferator-activated receptor-gamma (PPARgamma) plays a role in adipocyte differentiation and insulin sensitization. We identified and characterized a new C/T substitution at position -689 (-689C>T) in the P2 promoter of PPARgamma in a putative GATA binding site. By electrophoretic mobility shift assay, both GATA2 and GATA3 proteins could bind weakly to the wild-type P2 -689 GATA binding site but not...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15896659
DOI: 10.1016/j.ymgme.2005.02.004

Genes

GATA2
GATA3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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