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Article

A Functional Polymorphism in a STAT5B Site of the Human <i>PPARγ3</i> Gene Promoter Affects Height and Lipid Metabolism in a French Population

1 Feb 2003

Abstract excerpt

OBJECTIVE: The peroxisome proliferator-activated receptor-gamma (PPARgamma) plays a role in adipocyte differentiation and insulin sensitization. It has been shown that genetic variation in the PPARgamma gene alters body weight control, lipid and insulin homeostasis, and the susceptibility to type 2 diabetes. Four PPARgamma isoforms are generated by alternative splicing and promoter usage. PPARgamma3 is only...

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Share to Adipokines, Inflammation, and Metabolic Diseases
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Identifiers

PMID: 12588773
DOI: 10.1161/01.atv.0000051382.28752.fe

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