Article
Influence of CYP11B2 gene polymorphism on the prevalence of hypertension and the blood pressure in Japanese men: interaction with dietary salt intake.
Journal of nutrigenetics and nutrigenomics - 1 Jan 2008
Song Yixuan, Miyaki Koichi, Araki Jungo, Zhang Ling, Takahashi Yoshimitsu, Nakayama Takeo, Muramatsu Masaaki
Abstract excerpt
AIMS: CYP11B2 gene encodes a key enzyme for the production of aldosterone. Our aim is to investigate the association of -344T/C polymorphism with hypertension in Japanese men. The interaction between genotypes and dietary salt intake was also considered. METHODS: Three hundred and ten Japanese male workers participated in this study. Daily salt intake was calculated from a food frequency questionnaire. Melting...
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