Article
CSK negatively regulates nerve growth factor induced neural differentiation and augments AKT kinase activity.
Experimental cell research - 1 Jul 2005
Dey Nandini, Howell Brian W, De Pradip K, Durden Donald L
Abstract excerpt
Src family kinases are involved in transducing growth factor signals for cellular differentiation and proliferation in a variety of cell types. The activity of all Src family kinases (SFKs) is controlled by phosphorylation at their C-terminal 527-tyrosine residue by C-terminal SRC kinase, CSK. There is a paucity of information regarding the role of CSK and/or specific Src family kinases in neuronal...
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