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Article

Role of Pseudomonas aeruginosa quorum-sensing systems in a mouse model of chronic respiratory infection.

Journal of medical microbiology - 1 Jun 2005

Imamura Yoshifumi, Yanagihara Katsunori, Tomono Kazunori, Ohno Hideaki, Higashiyama Yasuhito, Miyazaki Yoshitsugu, Hirakata Yoichi, Mizuta Yohei, Kadota Jun-Ichi, Tsukamoto Kazuhiro, Kohno Shigeru

Abstract excerpt

The role of quorum-sensing systems in a mouse model of chronic Pseudomonas aeruginosa infection was studied. A chronic P. aeruginosa respiratory infection model was established by placement of a tube pre-coated with strain PAO1 (wild-type) or a quorum-sensing mutant, namely PAO-JP1 (Delta lasI), PDO100 (Delta rhlI) or PAO-JP2 (Delta lasI/Delta rhlI), in the bronchus. At day 14 after infection, the numbers of...

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PMID: 15888457
DOI: 10.1099/jmm.0.46004-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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