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Article

Role of the quorum-sensing system in experimental pneumonia due to Pseudomonas aeruginosa in rats.

American journal of respiratory and critical care medicine - 1 Jun 2003

Lesprit Philippe, Faurisson Francois, Join-Lambert Olivier, Roudot-Thoraval Francoise, Foglino Maryline, Vissuzaine Christiane, Carbon Claude

Abstract excerpt

The virulence of Pseudomonas aeruginosa is partly controlled by the las quorum-sensing system. A rat model of acute pneumonia was used to investigate the pathophysiological impact of this system by comparing the virulence of the wild-type virulent laboratory strain PAO1 with that of its lasR-dele...

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Identifiers

PMID: 12569080
DOI: 10.1164/rccm.200207-736BC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12569080-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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