Article

A longitudinal evaluation of localised chronic <i>Pseudomonas aeruginosa</i> infection in cystic fibrosis rat models

2025-04-17

Abstract excerpt

Recurrent bacterial infections with Pseudomonas aeruginosa result in chronic airway inflammation, lung damage and eventual respiratory failure, and are the major cause of morbidity and mortality in people with cystic fibrosis (CF). Animal models are essential for understanding disease progression and assessing potential treatments in the presence of infection. Previously reported P. aeruginosa lung infection rod...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 250b02b6-7825-521c-9a9f-b2b3eb19973e
DOI: 10.1101/2025.04.11.647899

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

A longitudinal evaluation of localised chronic <i>Pseudomonas aeruginosa</i> infection in cystic fibrosis rat modelsDOI 10.1101/2025.04.11.647899Read

An <i>ex vivo</i> cystic fibrosis model recapitulates key clinical aspects of chronic <i>Staphylococcus aureus</i> infectionSemantic proximity Read

A novel mouse model of chronic Pseudomonas aeruginosa infection inducing bronchiectasis-like phenotype.Semantic proximity Read

A chronic <i>Pseudomonas aeruginosa</i> mouse lung infection modeling the pathophysiology and inflammation of human cystic fibrosisSemantic proximity Read

An <i>ex vivo</i> lung model to study bronchioles infected with <i>Pseudomonas aeruginosa</i> biofilmsSemantic proximity Read

Pathogen–Host Interactions in <i>Pseudomonas aeruginosa</i> PneumoniaSemantic proximity Read

Transcriptome analysis of <i>Pseudomonas aeruginosa</i> biofilm infection in an <i>ex vivo</i> pig model of the cystic fibrosis lungSemantic proximity Read

Transcriptome Analysis of Pseudomonas aeruginosa Biofilm Infection in an Ex Vivo Pig Model of the Cystic Fibrosis LungSemantic proximity Read

Cystic fibrosis lung environment and Pseudomonas aeruginosa infection.Semantic proximity Read

Novel Therapeutic Strategies Applied to Pseudomonas aeruginosa Infections in Cystic FibrosisSemantic proximity Read

Tracking the immunopathological response to Pseudomonas aeruginosa during respiratory infectionsSemantic proximity Read

How long does it take to cue a <i>Pseudomonas aeruginosa</i> chronic infection phenotype in the lab? Insights from transcriptome analysis in a cystic fibrosis lung modelSemantic proximity Read

Mouse models of chronic lung infection withPseudomonas Aeruginosa: Models for the study of cystic fibrosisSemantic proximity Read