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Article

Contribution of quorum sensing to the virulence of Pseudomonas aeruginosa in burn wound infections.

Infection and immunity - 1 Nov 1999

Rumbaugh K P, Griswold J A, Iglewski B H, Hamood A N

Abstract excerpt

The Pseudomonas aeruginosa quorum-sensing systems, las and rhl, control the production of numerous virulence factors. In this study, we have used the burned-mouse model to examine the contribution of quorum-sensing systems to the pathogenesis of P. aeruginosa infections in burn wounds. Different quorum-sensing mutants of P. aeruginosa PAO1 that were defective in the lasR, lasI, or rhlI gene or both the lasI and...

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Identifiers

PMID: 10531240
DOI: 10.1128/IAI.67.11.5854-5862.1999
PMCID: PMC96966

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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