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Article

PTCH codon 1315 polymorphism and risk for nonmelanoma skin cancer.

The British journal of dermatology - 1 May 2005

Asplund A, Gustafsson A C, Wikonkal N M, Sela A, Leffell D J, Kidd K, Lundeberg J, Brash D E, Pontén F

Abstract excerpt

BACKGROUND: The PTCH tumour suppressor gene is involved in the development of nearly all basal cell carcinomas (BCCs) of the skin and a fraction of squamous cell carcinomas (SCCs). A nonconservative Pro/Leu nucleotide polymorphism within PTCH exon 23 at codon 1315 was recently reported to be potentially important for the development of breast epithelial cell cancers. Objectives Accordingly, the status of PTCH...

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Identifiers

PMID: 15888139
DOI: 10.1111/j.1365-2133.2005.06464.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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