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Article

Susceptibility to basal cell carcinoma: associations with PTCH polymorphisms.

Annals of human genetics - 1 Nov 2004

Strange R C, El-Genidy N, Ramachandran S, Lovatt T J, Fryer A A, Smith A G, Lear J T, Wong C, Jones P W, Ichii-Jones F, Hoban P R

Abstract excerpt

Loss of function of the human patched gene (PTCH) is common and critical in basal cell carcinoma (BCC) development. Indirect evidence suggests polymorphism in PTCH mediates BCC risk. We studied 659 BCC cases and 300 controls to determine if exon 2(318), 3(429), 11(1552), 12(1665), 12(1686), 14(2199) and 23(3944) and intron 9(1336-135) and 15(2560+9)PTCH variants were sufficiently common for use in case-control...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 15598212
DOI: 10.1046/j.1529-8817.2004.00132.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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