Article
Insights into TOR function and rapamycin response: chemical genomic profiling by using a high-density cell array method.
Proceedings of the National Academy of Sciences of the United States of America - 17 May 2005
Xie Michael W, Jin Fulai, Hwang Heejun, Hwang Seungmin, Anand Vikram, Duncan Mara C, Huang Jing
Abstract excerpt
With the advent of complete genome sequences, large-scale functional analyses are generating new excitement in biology and medicine. To facilitate genomewide functional analyses, we developed a high-density cell array with quantitative and automated readout of cell fitness. Able to print at > x 10 higher density on a standard microtiter plate area than currently possible, our cell array allows single-plate...
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