Article
Association between the 8473T>C polymorphism of PTGS2 and prostate cancer risk: a metaanalysis including 24,716 subjects.
Onkologie - 1 Jan 2013
Yang Xueling, Li Bo, Si Tongguo, Liu Ya, Guo Zhi
Abstract excerpt
BACKGROUND: Prostaglandin endoperoxide synthase 2 (PTGS2) is involved in prostate cancer (PCa) by stimulating cell proliferation, promoting angiogenesis, inhibiting apoptosis, and mediating immune suppression. 8473T>C, located in the 3' UTR of the PTGS2 gene, has been considered to influence PCa risk. METHODS: We searched Medline, PubMed, Elsevier, and Web of Science (updated to February 5, 2012) using the...
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