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Article

Association between cyclooxygenase-2 (COX-2) 8473 T > C polymorphism and cancer risk: a meta-analysis and trial sequential analysis.

BMC cancer - 24 Aug 2018

Li Qiuping, Ma Chao, Zhang Zhihui, Chen Suhua, Zhi Weiguo, Zhang Lei, Zhang Guoyao, Shi Lei, Cao Fei, Ma Tianjiang

Abstract excerpt

BACKGROUND: Numerous studies have investigated the relationship between COX-2 8473 T > C polymorphism and cancer susceptibility, however, the results remain controversial. Therefore, we carried out the present meta-analysis to obtain a more accurate assessment of this potential association. METHODS: In this meta-analysis, 79 case-control studies were included with a total of 38,634 cases and 55,206 controls. We...

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Identifiers

PMID: 30143023
DOI: 10.1186/s12885-018-4753-3
PMCID: PMC6109290

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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