Article
Brl1p -- a novel nuclear envelope protein required for nuclear transport.
Traffic (Copenhagen, Denmark) - 1 Jun 2005
Saitoh Yoh-Hei, Ogawa Kaoru, Nishimoto Takeharu
Abstract excerpt
In this article, we identify a cold-sensitive mutant of Xpo1p designated as xop1-2 (but will be referred to from here on as xpo1-ok) that is synthetically lethal with srm1-1, a Saccharomyces cerevisiae RCC1 homolog. xpo1-ok was a novel mutated allele with a single point mutation, T283P. Suppressors of xpo1-ok were isolated, and one of them was found to encode a novel nuclear envelope integral membrane protein...
Topics
- Active Transport, Cell Nucleus
- Amino Acid Sequence
- Biological Transport
- Cell Membrane
- Cell Nucleus
- Cell Proliferation
- DNA-Binding Proteins
- Genotype
- Green Fluorescent Proteins
- Guanine Nucleotide Exchange Factors
- In Situ Hybridization
- Karyopherins
- Membrane Proteins